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Faculty of Sciences
Document Details
Document Type
:
Article In Journal
Document Title
:
Micellization and Interfacial Behavior of the Sodium Salt of Ibuprofen-BRIJ-58 in Aqueous/Brine Solutions
Micellization and Interfacial Behavior of the Sodium Salt of Ibuprofen-BRIJ-58 in Aqueous/Brine Solutions
Document Language
:
English
Abstract
:
This work deals with the effect of a nonionic surfactant (BRIJ-58) on the physicochemical properties of the sodium salt of ibuprofen, in the absence and presence of salt (NaCl), in order to understand the nature of interactions in IBF-BRIJ-58 aqueous mixtures. Tensiometric measurements were carried out to estimate the critical micelle concentrations (cmc) of drug and surfactant along with their mixtures. A gradual reduction in the surface charge of the micelles was obtained by adding salt followed by the early formation of the micelles; hence, the cmc value of the amphiphiles decreased. Various parameters such as micellar, interfacial, corresponding thermodynamic parameters, etc., have been calculated and are discussed in detail by applying various theoretical models reported in the literature. The theories of Clint, Rubingh, Motomura and Maeda have been applied to investigate interactions among the components. Structural parameters proposed by Tanford have also been also evaluated.
ISSN
:
0095-9782
Journal Name
:
JOURNAL OF SOLUTION CHEMISTRY
Volume
:
45
Issue Number
:
5
Publishing Year
:
1437 AH
2016 AD
Article Type
:
Article
Added Date
:
Wednesday, August 9, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
N (Azum
(Azum, N
Researcher
M Rub
Rub, M
Researcher
A Asiri
Asiri, A
Researcher
Files
File Name
Type
Description
42526.pdf
pdf
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