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Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
Effects of Honey on Stress-Induced Ulcers in Rats
Effects of Honey on Stress-Induced Ulcers in Rats
Document Language
:
English
Abstract
:
The effects of honey on stress-induced ulcers were examined in rats. Stress was induced by using the Strain and Water Immersion technique (6 hours). Ulcer incidence and severity were quantified by an ulcer index.A honey solution, which consisted of 40% honey in water, was administered orally in dose-volumes of 1,3, 5.7 and 14 mt/kg, 20 mm before stress induction in 48 hr-fasting rats. Control rats receivedequivalent volumes of a Honey Control Solution (HCS). The systemic effects of honey on stress induced ulcers were examined by intraperitoneal injection of hcuxey (3.5 mt/kg) 10 mm. before stress induction. The effect of a honey solution on gastro-mntestinal tract motility was examined by using a charcoal meal incorporated with honey or tiCS. Results show that intraluminal honey administration lowers the incidence of stress-induced ulcers by 15% relative to that of control rats who received saline (X2 = 3.1, P = .07). Rats pretreated with a honey solution (3,5,7 and 14 mt/kg) showed a significantly lower ulcer index than HCS-pretreated rats (P < .05). Incorporation of honey into a charcoal meal lowers G.LT. stress-induced hypermotility by 37.8% of matched control received saline incorporated charcoal meal. It was concluded that intraluminal administration of honey decreases the severity of stress-induced ulcers in rats
ISSN
:
1319-1004
Journal Name
:
Medical Science Journal
Volume
:
7
Issue Number
:
1
Publishing Year
:
1419 AH
1999 AD
Article Type
:
Article
Added Date
:
Friday, April 20, 2012
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
عدنان المزروع
Al-Mazrooa, Adnan
Investigator
Doctorate
منصور سليمان
Sulaiman, Mansour
Researcher
Doctorate
Files
File Name
Type
Description
32917.pdf
pdf
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