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Document Details
Document Type
:
Article In Journal
Document Title
:
Effects of starvation and streptozotocin-induced diabetes on the activity of phosphofructokinase in the epithelial cells of rat colon
Effects of starvation and streptozotocin-induced diabetes on the activity of phosphofructokinase in the epithelial cells of rat colon
Subject
:
Biochemistry
Document Language
:
English
Abstract
:
The regulation of phosphofructokinase in the colonic mucosa of 48 h-starved and streptozotocin-induced diabetic rats was investigated. The specific activities of phosphofructokinase from colonic mucosa of starved and diabetic rats were found to be diminished compared with normal controls. The enzyme obtained from the colonic mucosa of normal, diabetic and starved rats showed sigmoidal velocity curves with respect to fructose-6-phosphate, with apparent Km values of 0.6, 0.62 and 0.7 mM, respectively. However, the present results indicated that phosphofructokinase from the epithelial cells of rat colon is not regulated in a manner similar to that of the intestinal enzyme, which was shown to be highly regulated
ISSN
:
1638-6183
Journal Name
:
Biochimie
Volume
:
70
Issue Number
:
6
Publishing Year
:
1408 AH
1988 AD
Article Type
:
Article
Added Date
:
Saturday, December 3, 2011
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
محمد العرضاوي
Ardawi, Mohammed
Researcher
Doctorate
Files
File Name
Type
Description
31510.pdf
pdf
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