Document Details

Document Type : Article In Journal 
Document Title :
Changes in serum lipids of mice experimentally infected with Schistosoma mansoni
Changes in serum lipids of mice experimentally infected with Schistosoma mansoni
 
Subject : Biochemistry 
Document Language : English 
Abstract : Serum samples of mice infected with 80 cercariae of Schistosoma mansoni for different time periods (2-20 weeks) were used in this study. It was observed that the concentrations of serum total cholesterol and triacylglycerol decreased significantly (P < 0.001, P < 0.0001 respectively) in infected as compared to control mice starting from the fourth week post infection. Similarly, the concentration of serum high density lipoprotein-cholesterol (HDL-C) decreased significantly (P > 0.001) in infected as compared to control mice. However, the serum lipoproteins profile was variable at different stages of infection. On the other hand, the liver weight increased significantly (P < 0.0001) in infected as compared to control mice starting from the sixth week post infection. These changes might be attributed to several metabolites released by S. mansoni which affect the host hepatic tissue resulting in decreased synthesis of these parameters and their release into the circulation 
ISSN : 0253-5890 
Journal Name : Journal of the Egyptian Society of Parasitology 
Volume : 27 
Issue Number : 2 
Publishing Year : 1418 AH
1997 AD 
Article Type : Article 
Added Date : Friday, December 2, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
زهير المرزوقيMarzouki, Zohair InvestigatorDoctorate 
عدنان أمينAmin, Adnan ResearcherDoctorate 

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