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Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
Lack of detection of human papillomavirus infection by hybridization test in prostatic biopsies
Lack of detection of human papillomavirus infection by hybridization test in prostatic biopsies
Subject
:
Virology
Document Language
:
English
Abstract
:
OBJECTIVE: To explore the possibility of finding human papillomavirus (HPV) infection in the prostate tissue of a cohort of Saudi men presenting with benign prostatic hyperplasia (BPH) or prostate cancer. METHODS: A cohort study on prospectively collected tissue samples was conducted at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from March 2007 to December 2008 on a total of 56 male patients, age range 50-93 years (average 68), diagnosed as having BPH or prostate cancer. The HPV DNA hybridization by hybrid capture 2 technology was performed on prostate biopsies of these patients to detect 18 types of HPV infection, and differentiate between 2 HPV DNA groups, the low-risk types, and the high/intermediate risk types. RESULTS: The tissues of all the prostatic biopsies were negative for HPV DNA. CONCLUSION: Our results, using the hybridization test, indicate that it is unlikely that HPV-16 or HPV-18, or the other tested subtypes, enhance the risk of prostate cancer
ISSN
:
0379-5284
Journal Name
:
The Saudi Medical Journal
Volume
:
30
Issue Number
:
5
Publishing Year
:
1430 AH
2009 AD
Article Type
:
Article
Added Date
:
Sunday, July 10, 2011
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
فاتن قزاز
Gazzaz, Faten
Investigator
Doctorate
fatengazzaz@hotmail.com
هشام موصلي
Mosli, Hisham
Researcher
Doctorate
Files
File Name
Type
Description
29940.pdf
pdf
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