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Deanship of Scientific Research
Document Details
Document Type
:
Project
Document Title
:
An ideal selective anticancer agent
علاج جديد يهاجم الخلايا السرطانية دون غيرها
Subject
:
An ideal selective anticancer agent
Document Language
:
Arabic
Abstract
:
PM 701 is a natural product which is clean, sterile and it is free of toxicity. It was studied by our team work in the previous research project (A New Alternative Medicine can cause Selective Cell Death in Cancer Cells). We used PM 701, in previous part as anticancer agent, it cause selective programmed cell death of cancer cell (Apoptosis) at tissue culture study of human lung cancer cells A549, while it has reparative effect on normal human cell (fibroblasts). It shows the same effect on leukemia cells (1210) at tissue culture level. Also it was very effective in limiting of metastasic spreading of leukemia cells (L1210) at in vivo level, on animal models. The apoptosis was studied with different method, e.g. with MTT. We also studied cancer on animal model histopathologicaly with light and electron microcopies. This study will include experimental studies on cancer cells as in vitro (tissue culture) and on animal as in vivo. The invitro study will inv olve study the effect of PM 701 on breast cancer and skin cancer cell at tissue culture level. The in vivo experiment will be study the effect of PM 701 on animal after production of breast cancer or skin cancer on animal model using different implantation technique. The last step of this experiment will be the use of this agent as topical treatment and oral therapy for volunteer patients to see its effect on humans, and after ethical committee approval.
Publishing Year
:
1427 AH
2006 AD
Sponsor Name
:
King Abdulaziz University
Sponsorship Year
:
1427 AH
2006 AD
Added Date
:
Sunday, June 27, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
فاتن عبد الرحمن خورشيد
Khorshid, Faten Abdul Rahman
Investigator
Doctorate
Files
File Name
Type
Description
27127.docx
docx
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