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Document Details
Document Type
:
Article In Journal
Document Title
:
NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS
NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS
Document Language
:
English
Abstract
:
Background: systemic lupus erythematosus (SLE) is a multisystem disease of unclear eitiology .Neutropenia occurs in approximately half of SLE patients .Infection is a major cause of morbidity and mortality in those SLE patients . Multiple causes have been involved in the increased susceptibility to infection in such patients. Objectives : This study was conducted to document the frequency of neutropenia and its implication on infection risk among our SLE patients. Methodology: Retrospectively, we studied 61 SLE patients from January 2000 to December 2005. Information collected included age, sex, nationality, absolute neutrophil count and history of infection before treatment. Results: Sixty one patients were found to have SLE, 91.8% were females, while males were 8.2% with a female to male ratio of 11.2:1. The mean age of SLE patients was 26.27 years with a SD + 10.06.Neutropenia was found in 47.4% of patients, 69% of them had moderate to severe type.Infections were documented in 31.1% of SLE patients, 63.1% of them were neutropenic. Urinary tracts followed by chest were the two main sites for infection. Conclusion: In the current study, neutropia is common among our SLE patients. Infection was demonstrated in about one third of the cases, the majority of them were neutropenic. However, neutropenia is one among multiple causes for decreases resistance to infection in untreated active SLE patients.
ISSN
:
1319-1004
Journal Name
:
Egypt Rheumatol Rehabilitation
Volume
:
33
Issue Number
:
1
Publishing Year
:
1426 AH
2006 AD
Article Type
:
Article
Added Date
:
Sunday, April 18, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
العنود الجفري
AL-JIFRI, AL-ANOUD
Researcher
Doctorate
anoud_jif@hotmail.com
فاتن السايس
AL-SAYES, FATIN
Researcher
Doctorate
fatinsayes@yahoo.com
Files
File Name
Type
Description
26544.doc
doc
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