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Document Details
Document Type
:
Article In Journal
Document Title
:
Effects of Local Heating of the Testes on the Concentration of Testosterone in Jugular and Testicular Venous Blood of Rats and on Testosterone Production in vitro. Intern. J. Androl.
Effects of Local Heating of the Testes on the Concentration of Testosterone in Jugular and Testicular Venous Blood of Rats and on Testosterone Production in vitro. Intern. J. Androl.
Document Language
:
English
Abstract
:
Heating both testes of rats to between 39oC and 41oC for 30 min was apparently without effect 21 days later, but heating to between 41.5oC and 43oC for 30 min resulted in a significant drop in testis weight accompanied by significant rises in the serum levels of LH and FSH. There were no changes in serum testosterone concentration in the peripheral circulation although there were increases in the concentration in testicular venous blood. The ability of the heated testis to secrete testosterone in vivo in response to maximal stimulation by hCG was reduced, as judged by testosterone levels in peripheral blood, while there was a supranormal increase in testosterone levels in testicular venous blood. Maximally stimulated testosterone production in vitro by the heated testis was supranormal whereas the basal production of testosterone per testis was not different from control values. Therefore, it appears that the testosterone produced by Leydig cells from heated testes may not be secreted as effectively as in normal testes.
ISSN
:
1059-7794
Journal Name
:
International Journal of Andrology
Volume
:
11
Issue Number
:
2
Publishing Year
:
1988 AH
1988 AD
Article Type
:
Article
Added Date
:
Monday, March 15, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
خضر عبدالجليل
Abdel Galil, Khidir
Researcher
Doctorate
Files
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Type
Description
25986.doc
doc
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