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Document Details
Document Type
:
Article In Journal
Document Title
:
Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
Document Language
:
English
Abstract
:
AIM: To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. METHODS: 19 patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. RESULTS: 8/19 patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. CONCLUSION: Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated.
ISSN
:
1468-2079
Journal Name
:
British Journal of Ophthalmology
Volume
:
85
Issue Number
:
10
Publishing Year
:
1422 AH
2001 AD
Article Type
:
Article
Added Date
:
Monday, August 31, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سعد وهيب
Waheeb, Saad
Researcher
Doctorate
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28972.pdf
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