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Document Details
Document Type
:
Article In Journal
Document Title
:
Defective Collagen Metabolism in Saudi Patients with Hernia
Defective Collagen Metabolism in Saudi Patients with Hernia
Subject
:
General Surgery
Document Language
:
English
Abstract
:
Fibroblastic cell cultures were derived from the hernial sac and some of the surrounding muscles (rectus sheath, internal oblique, and/or cremasteric muscle) of 130 Saudi patients with different types of herniation, and from 21 control subjects. The rates of cell proliferation were studied for 39 days. Results suggested decreased rates of proliferation of cells derived from patients compared to controls. In vitro studies of the rates of incorporation of 14C proline into the muscle biopsies revealed decreased rates of label incorporation in the samples derived from patients compared to controls. However, no differences were detected between rates of collagenase activities of the biopsies obtained from patients compared to those of controls. These findings suggest that collagen synthesis is probably defective in the studied group of Saudi patients with hernia
ISSN
:
0004-5632
Journal Name
:
Annals of Clinical Biochemistry
Volume
:
29
Issue Number
:
4
Publishing Year
:
1412 AH
1992 AD
Article Type
:
Article
Added Date
:
Saturday, August 22, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
محمد عجب نور
Ajabnoor, Mohammed
Investigator
Doctorate
أحمد مختار
Mokhtar, Ahmed
Researcher
Doctorate
عادل عبدالرافع
AbdulRafee, Adel
Researcher
Doctorate
علي طه
Taha, Ali
Researcher
Doctorate
Files
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Type
Description
29340.zip
zip
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